Fertility/Hormonal

A Simple Blood Test Marker to Determine Ovarian Reserve

Measurement of ovarian reserve is of interest to women in general, and assessment of ovarian reserve may provide insight into the remaining number of fertile years a woman has.  The Anti-Mullerian Hormone (AMH) is an endocrine marker for quantitive prediction of ovarian reserve, ovarian aging, ovarian dysfunction and ovarian responsiveness.

In instances of Polycystic Ovary Syndrome (PCOS), a well-recognised endocrine disorder in women of reproductive age, a two or three fold increase in growing follicles would be reflected in a two or three fold increase in blood AMH levels.  The Anti-Mullerian Hormone test can therefore be beneficial in the diagnosis of PCOS and as a marker for the patient’s response to treatment.

Evaluating Fertility Potential

Blood AMH levels correlate with the number of antral follicles with great specificity than inhibit B, Oestradiol, Follicle Stimulating Hormone and Luteinizing Hormone on day 3 of the cycle.  Therefore, day 3 AMH levels may reflect ovarian status better than the usual hormone markers mentioned.

Diminished ovarian reserve, associated with poor response to in vitro fertilization, is signalled by reduced baseline serum AMH concentrations.  AMH would appear to be a useful marker for predicting ovarian aging and the potential for successful IVF.

The duration of the menopausal transition can vary significantly in individual women, and reproductive capacity may be compromised before hormonal imbalances are evident.  AMH levels can predict the occurrence of the menopausal transition.

Assessing Polycystic Ovary Syndrome (PCOS)

Blood AMH levels are elevated in patients with Polycystic Ovary Syndrome and may be useful as a marker for the extent of the disease and the progress of treatment.

FEMALE INFERTILITY PROFILE

LH

FSH

Prolactin

Oestradiol (17-Beta)

MALE INFERTILITY PROFILE

FSH

LH

Testosterone

Free Androgen Index

Prolactin

SHBG